|
Neoplastic Syndromes, Hereditary
|
0.170 |
GeneticVariation
|
group |
BEFREE |
Li-Fraumeni syndrome (LFS) is an autosomal dominant hereditary cancer syndrome associated with germline mutations in the TP53 gene and a high risk of childhood-onset malignancies.
|
29077256 |
2018 |
|
Neoplastic Syndromes, Hereditary
|
0.170 |
GeneticVariation
|
group |
CLINVAR |
TP53 germline and somatic mutations in a patient with fibrolamellar hepatocellular carcinoma.
|
28477317 |
2018 |
|
Neoplastic Syndromes, Hereditary
|
0.170 |
GeneticVariation
|
group |
CLINVAR |
Clinical characteristics and registry-validated extended pedigrees of germline TP53 mutation carriers in Denmark.
|
29324801 |
2018 |
|
Neoplastic Syndromes, Hereditary
|
0.170 |
GeneticVariation
|
group |
CLINVAR |
Expression of circulating miRNAs associated with lymphocyte differentiation and activation in CLL-another piece in the puzzle.
|
27730344 |
2017 |
|
Neoplastic Syndromes, Hereditary
|
0.170 |
GeneticVariation
|
group |
CLINVAR |
A novel TP53 germline inframe deletion identified in a Spanish series of Li-fraumeni syndrome suspected families.
|
28573494 |
2017 |
|
Neoplastic Syndromes, Hereditary
|
0.170 |
GeneticVariation
|
group |
CLINVAR |
The frequency of cancer predisposition gene mutations in hereditary breast and ovarian cancer patients in Taiwan: From BRCA1/2 to multi-gene panels.
|
28961279 |
2017 |
|
Neoplastic Syndromes, Hereditary
|
0.170 |
CausalMutation
|
group |
CLINVAR |
Constitutional mosaicism of a de novo TP53 mutation in a patient with bilateral choroid plexus carcinoma.
|
29025599 |
2017 |
|
Neoplastic Syndromes, Hereditary
|
0.170 |
CausalMutation
|
group |
CLINVAR |
Germline TP53 mutations result into a constitutive defect of p53 DNA binding and transcriptional response to DNA damage.
|
28472496 |
2017 |
|
Neoplastic Syndromes, Hereditary
|
0.170 |
GeneticVariation
|
group |
CLINVAR |
Genomic analysis of inherited breast cancer among Palestinian women: Genetic heterogeneity and a founder mutation in TP53.
|
28486781 |
2017 |
|
Neoplastic Syndromes, Hereditary
|
0.170 |
GeneticVariation
|
group |
CLINVAR |
Surveillance in Germline TP53 Mutation Carriers Utilizing Whole-Body Magnetic Resonance Imaging.
|
28772290 |
2017 |
|
Neoplastic Syndromes, Hereditary
|
0.170 |
GeneticVariation
|
group |
CLINVAR |
Synonymous Somatic Variants in Human Cancer Are Not Infamous: A Plea for Full Disclosure in Databases and Publications.
|
28026089 |
2017 |
|
Neoplastic Syndromes, Hereditary
|
0.170 |
GeneticVariation
|
group |
CLINVAR |
Germline Mutations in Cancer Susceptibility Genes in a Large Series of Unselected Breast Cancer Patients.
|
28724667 |
2017 |
|
Neoplastic Syndromes, Hereditary
|
0.170 |
GeneticVariation
|
group |
CLINVAR |
Germline TP53 mutations result into a constitutive defect of p53 DNA binding and transcriptional response to DNA damage.
|
28369373 |
2017 |
|
Neoplastic Syndromes, Hereditary
|
0.170 |
CausalMutation
|
group |
CLINVAR |
TP53 and CDKN1A mutation analysis in families with Li-Fraumeni and Li-Fraumeni like syndromes.
|
27714481 |
2017 |
|
Neoplastic Syndromes, Hereditary
|
0.170 |
CausalMutation
|
group |
CLINVAR |
Li-Fraumeni syndrome presenting as mucosal melanoma: Case report and treatment considerations.
|
27726232 |
2017 |
|
Neoplastic Syndromes, Hereditary
|
0.170 |
CausalMutation
|
group |
CLINVAR |
Somatic and Germline TP53 Alterations in Second Malignant Neoplasms from Pediatric Cancer Survivors.
|
27683180 |
2017 |
|
Neoplastic Syndromes, Hereditary
|
0.170 |
GeneticVariation
|
group |
CLINVAR |
Deleterious Germline Mutations in Patients With Apparently Sporadic Pancreatic Adenocarcinoma.
|
28767289 |
2017 |
|
Neoplastic Syndromes, Hereditary
|
0.170 |
CausalMutation
|
group |
CLINVAR |
Baseline results from the UK SIGNIFY study: a whole-body MRI screening study in TP53 mutation carriers and matched controls.
|
28091804 |
2017 |
|
Neoplastic Syndromes, Hereditary
|
0.170 |
CausalMutation
|
group |
CLINVAR |
Targeted next-generation sequencing of pediatric neuro-oncology patients improves diagnosis, identifies pathogenic germline mutations, and directs targeted therapy.
|
28453743 |
2017 |
|
Neoplastic Syndromes, Hereditary
|
0.170 |
CausalMutation
|
group |
CLINVAR |
Germline Mutations in Cancer Susceptibility Genes in a Large Series of Unselected Breast Cancer Patients.
|
28724667 |
2017 |
|
Neoplastic Syndromes, Hereditary
|
0.170 |
GeneticVariation
|
group |
CLINVAR |
Gene panel sequencing in familial breast/ovarian cancer patients identifies multiple novel mutations also in genes others than BRCA1/2.
|
27616075 |
2017 |
|
Neoplastic Syndromes, Hereditary
|
0.170 |
GeneticVariation
|
group |
CLINVAR |
Recurrent TP53 missense mutation in cancer patients of Arab descent.
|
27866339 |
2017 |
|
Neoplastic Syndromes, Hereditary
|
0.170 |
CausalMutation
|
group |
CLINVAR |
USP7 inhibitors, downregulating CCDC6, sensitize lung neuroendocrine cancer cells to PARP-inhibitor drugs.
|
27372520 |
2017 |
|
Neoplastic Syndromes, Hereditary
|
0.170 |
GeneticVariation
|
group |
CLINVAR |
Targeted sequencing of refractory myeloma reveals a high incidence of mutations in CRBN and Ras pathway genes.
|
27458004 |
2016 |
|
Neoplastic Syndromes, Hereditary
|
0.170 |
CausalMutation
|
group |
CLINVAR |
Multiple primary tumors in a family with Li-Fraumeni syndrome with a TP53 germline mutation identified by next-generation sequencing.
|
27516001 |
2016 |