TP53, tumor protein p53, 7157

N. diseases: 2494; N. variants: 527
Disease: Neuralgia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0027796
Disease: Neuralgia
Neuralgia 		0.040 Biomarker phenotype BEFREE Our results showed that both IL-6 and Jun genes and the signaling pathway of MAPK, apoptosis, P53 present their vital modulatory role in nerve regeneration and neuropathic pain. 29672183 2020
CUI: C0027796
Disease: Neuralgia
Neuralgia 		0.040 Biomarker phenotype BEFREE Fos, Tp53, Csk, and Map2k2 might be the potential biomarkers related to neuropathic pain. 31352588 2019
CUI: C0027796
Disease: Neuralgia
Neuralgia 		0.040 Biomarker phenotype BEFREE Dysregulation of p53 and Parkin Induce Mitochondrial Dysfunction and Leads to the Diabetic Neuropathic Pain. 31377450 2019
CUI: C0027796
Disease: Neuralgia
Neuralgia 		0.040 Biomarker phenotype BEFREE Our results showed that overexpression of the p53 gene, and the subsequent increase in caspase-3 expression, in dorsal root ganglion neurons led to increased apoptotic changes in these neurons. p53 may therefore be partly responsible for the development of chronic constriction injury-induced NP. 30233637 2018