TP53, tumor protein p53, 7157

N. diseases: 2494; N. variants: 527
Disease: Sarcoma, Spindle Cell ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0205945
Disease: Sarcoma, Spindle Cell
Sarcoma, Spindle Cell 		0.510 GeneticVariation disease BEFREE Here we show that when MDM2-ALT1 is ubiquitously expressed in p53 null mice it leads to increased incidence of spindle cell sarcomas, including RMS. 28892044 2018
CUI: C0205945
Disease: Sarcoma, Spindle Cell
Sarcoma, Spindle Cell 		0.510 Biomarker disease CTD_human Subtype-specific genomic alterations define new targets for soft-tissue sarcoma therapy. 20601955 2010
CUI: C0205945
Disease: Sarcoma, Spindle Cell
Sarcoma, Spindle Cell 		0.510 Biomarker disease CTD_mouse Aflatoxin B1 and/or hepatitis B virus induced tumor spectrum in a genetically engineered hepatitis B virus expression and Trp53 haploinsufficient mouse model system for hepatocarcinogenesis. 19258306 2009