TP53, tumor protein p53, 7157

N. diseases: 2494; N. variants: 527
Disease: Fibroblastic osteosarcoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0279602
Disease: Fibroblastic osteosarcoma
Fibroblastic osteosarcoma 		0.010 GeneticVariation disease BEFREE We and others have previously described murine models of osteosarcoma based on osteoblast-restricted Cre:lox deletion of Trp53 (p53) and Rb1 (Rb), resulting in a phenotype most similar to fibroblastic osteosarcoma in humans. 23486187 2013