TP53, tumor protein p53, 7157

N. diseases: 2494; N. variants: 527
Disease: Squamous cell carcinoma, microinvasive ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0334252
Disease: Squamous cell carcinoma, microinvasive
Squamous cell carcinoma, microinvasive 		0.010 AlteredExpression disease BEFREE Our results demonstrate that increased expression of the p53 protein is a common finding in both in situ and microinvasive squamous cell carcinoma of the skin, and they suggest that loss of normal p53 tumor suppressor activity may be an important mechanism of oncogenesis in these neoplasms. 7675772 1995