TP53, tumor protein p53, 7157

N. diseases: 2494; N. variants: 527
Disease: Vulval intraepithelial neoplasia grade 3 ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0349560
Disease: Vulval intraepithelial neoplasia grade 3
Vulval intraepithelial neoplasia grade 3 		0.020 Biomarker disease BEFREE There was a trend in p53 disruption associated with invasive disease; HPV-positive VSCC demonstrated more disruption than VIN associated with VSCC, which had more disruption than lone VIN III (22 vs 10 vs 0%, respectively, P<0.005). 12610510 2003
CUI: C0349560
Disease: Vulval intraepithelial neoplasia grade 3
Vulval intraepithelial neoplasia grade 3 		0.020 Biomarker disease BEFREE HPV and p53 were detected in 57.9 and 21.1% of the VIN III lesions, 33.3 and 66.7% of superficially invasive carcinomas, and 7.3 and 58.2% of invasive squamous cell carcinomas, respectively. 12937780 2003