TP53, tumor protein p53, 7157

N. diseases: 2494; N. variants: 527
Disease: Short telomere length ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C4531138
Disease: Short telomere length
Short telomere length 		0.030 GeneticVariation phenotype BEFREE Apart from identifying associations of short telomere length with adverse prognostic factors and survival, the study identified cases with 17p- and 11q- associated with TP53 and ATM loss, respectively, to have the shortest telomeres, even when these aberrations were present in small subclones. 30911113 2019
CUI: C4531138
Disease: Short telomere length
Short telomere length 		0.030 Biomarker phenotype BEFREE Taken together, these results indicate that short telomere length in peripheral blood leukocytes is a biomarker for ESCC risk, and has statistically additive effects with p53 variants and HPV seropositivity with regard to the risk of ESCC in a Han Chinese population. 25153662 2014
CUI: C4531138
Disease: Short telomere length
Short telomere length 		0.030 Biomarker phenotype BEFREE Short telomere length is associated with NOTCH1/SF3B1/TP53 aberrations and poor outcome in newly diagnosed chronic lymphocytic leukemia patients. 23620080 2013