C3, complement C3, 718

N. diseases: 343; N. variants: 49
Disease: Mitral and aortic incompetence ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0264774
Disease: Mitral and aortic incompetence
Mitral and aortic incompetence 		0.010 GeneticVariation disease BEFREE Salient features included mitral and aortic regurgitation that worsened during the acute illness, painful pericarditis, and high troponin; severe acute kidney injury with oliguria, hematuria, and macroalbuminuria; reduced complement (C3); and elevated streptococcal serology. 31516109 2019