C3, complement C3, 718

N. diseases: 343; N. variants: 49
Disease: Lupus Erythematosus ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0409974
Disease: Lupus Erythematosus
Lupus Erythematosus 		0.040 Biomarker disease BEFREE In this study, we investigate the effect of a novel complement C3 inhibitor, CRIg/FH, in the treatment of lupus nephropathy in MRL/lpr lupus mice. 31752725 2019
CUI: C0409974
Disease: Lupus Erythematosus
Lupus Erythematosus 		0.040 Biomarker disease BEFREE To investigate the clinical value of anti-Sm antibodies in diagnosis and monitoring of systemic lupus erythematosus (SLE) and their ability to predict lupus flares compared with that of anti-dsDNA antibody and complement (C3) assays. 28281463 2017
CUI: C0409974
Disease: Lupus Erythematosus
Lupus Erythematosus 		0.040 AlteredExpression disease BEFREE Complement C3 and C4 levels were consistently normal during flares of her lupus and haemolytic activity of her complement was absent, suggesting a deficiency of an early component of the complement cascade.No C1q could be detected. 10735963 2000
CUI: C0409974
Disease: Lupus Erythematosus
Lupus Erythematosus 		0.040 Biomarker disease BEFREE We conclude that the decreased number of C3b receptors in lupus is inherited, not acquired. 7110302 1982