Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0010346
Disease: Crohn Disease
Crohn Disease
0.020 AlteredExpression disease BEFREE Thus we investigated the yet-unknown expression and function of TAK1 in human CD-associated fibrosis. 26185333 2015
CUI: C0010346
Disease: Crohn Disease
Crohn Disease
0.020 GeneticVariation disease BEFREE MDP-induced tolerance was independent of receptor downregulation but was associated with reduced levels of phosphorylated TAK1 and abrogated phosphorylation of the downstream MAPK.Since Nod2 mutations have been associated with susceptibility to develop Crohn's disease (CD), we compared the MDP-induced tolerance in healthy donors and CD patients with compound heterozygous Nod2 mutations (Mut-Nod2) expressing variant NOD2 proteins. 19572373 2009