TRAF3, TNF receptor associated factor 3, 7187

N. diseases: 129; N. variants: 15
Disease: Osteopenia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0029453
Disease: Osteopenia
Osteopenia 		0.020 Biomarker disease BEFREE Development of drugs to prevent TRAF3 degradation in immune and bone cells could be a novel therapeutic approach to prevent or reduce bone loss and the incidence of several common diseases associated with aging. 30323820 2018
CUI: C0029453
Disease: Osteopenia
Osteopenia 		0.020 AlteredExpression disease BEFREE These findings suggest that upregulation of TRAF3 or NF-kappaB p100 expression or inhibition of NF-kappaB p100 degradation in OCPs could limit bone destruction and inflammation-induced bone loss in common bone diseases. 19770515 2009