TRAF6, TNF receptor associated factor 6, 7189

N. diseases: 254; N. variants: 10
Disease: Arthritis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0003864
Disease: Arthritis
Arthritis 		0.030 Biomarker disease BEFREE TRAF6 neddylation drives inflammatory arthritis by increasing NF-κB activation. 30626891 2019
CUI: C0003864
Disease: Arthritis
Arthritis 		0.030 AlteredExpression disease BEFREE The expressions of RANKL and DKK-1 increased in CIA rats as compared with those in the control; TRAF6 was up-regulated and β-catenin was down-regulated in the bone tissues of CIA rats. 30412852 2018
CUI: C0003864
Disease: Arthritis
Arthritis 		0.030 Biomarker disease BEFREE Inhibition of TRAF6 using mouse specific siTRAF6 reduced the severity of arthritis and joint inflammation. 25522907 2015