TRAF6, TNF receptor associated factor 6, 7189

N. diseases: 254; N. variants: 10
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0024143
Disease: Lupus Nephritis
Lupus Nephritis
0.040 AlteredExpression disease BEFREE MiR-146b-5p attenuated the inflammatory response of glomerular mesangial cells by inhibiting the expressions levels of TRAF6 and IRAK1 in lupus nephritis. 29630120 2018
CUI: C0024143
Disease: Lupus Nephritis
Lupus Nephritis
0.040 Biomarker disease BEFREE The effect of miR-146a and TRAF6 on LN recurrence was analyzed. 28549054 2017
CUI: C0024143
Disease: Lupus Nephritis
Lupus Nephritis
0.040 Biomarker disease BEFREE Dysregulation of miRNA-146a contributes to the development of lupus nephritis via targeting of TRAF6. 29754557 2017
CUI: C0024143
Disease: Lupus Nephritis
Lupus Nephritis
0.040 AlteredExpression disease BEFREE MiR-146a expression was significantly depressed in renal tissues of LN patients, while TRAF6 expression, macrophage infiltration and p-p65 expression were all elevated as the activity of LN was induced. 28338190 2017