TRAF6, TNF receptor associated factor 6, 7189

N. diseases: 254; N. variants: 10
Disease: melanoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0025202
Disease: melanoma
melanoma 		0.040 Biomarker disease BEFREE Identification and analyses of natural compounds as potential inhibitors of TRAF6-Basigin interactions in melanoma using structure-based virtual screening and molecular dynamics simulations. 30253283 2018
CUI: C0025202
Disease: melanoma
melanoma 		0.040 Biomarker disease BEFREE This makes TRAF6 a potential therapeutic target in melanoma. 28612997 2017
CUI: C0025202
Disease: melanoma
melanoma 		0.040 Biomarker disease BEFREE Taken together, our findings indicate that TRAF6 is involved in regulating melanoma invasion and metastasis, suggesting that TRAF6 may be a potential target for therapy or chemo-prevention in melanoma. 26769849 2016
CUI: C0025202
Disease: melanoma
melanoma 		0.040 Biomarker disease BEFREE Taken together, these findings show that EGCG is a novel E3 ubiquitin ligase inhibitor that could be used to target TRAF6 for chemotherapy or the prevention of melanoma. 27791197 2016