TRAF6, TNF receptor associated factor 6, 7189

N. diseases: 254; N. variants: 10
Disease: Ischemic stroke ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0948008
Disease: Ischemic stroke
Ischemic stroke 		0.040 AlteredExpression disease BEFREE MiR-146a/b could down-regulate the TRAF6 and IRAK1 expressions and promote proliferation, migration and angiogenesis ability of EPCs, which was important for recovery of patients with hyperacute ischemic stroke. 28811005 2017
CUI: C0948008
Disease: Ischemic stroke
Ischemic stroke 		0.040 Biomarker disease BEFREE The Ubiquitin E3 Ligase TRAF6 Exacerbates Ischemic Stroke by Ubiquitinating and Activating Rac1. 29114077 2017
CUI: C0948008
Disease: Ischemic stroke
Ischemic stroke 		0.040 GeneticVariation disease BEFREE This study aims to investigate the associations of TRAF6 gene polymorphisms with susceptibility to IS and IS-related quantitative traits in Southern Chinese Han population. 25999280 2015
CUI: C0948008
Disease: Ischemic stroke
Ischemic stroke 		0.040 Biomarker disease BEFREE We found that the MyD88-independent pathway and the ubiquitin-mediated proteolysis pathway, especially TRAF6, may be the most vital molecules among TLR downstream pathways in incidences of ischemic stroke. 23726813 2013