TRAF6, TNF receptor associated factor 6, 7189

N. diseases: 254; N. variants: 10
Disease: Adult Lymphoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1332206
Disease: Adult Lymphoma
Adult Lymphoma 		0.020 Biomarker disease BEFREE Smoothened stabilizes and protects TRAF6 from degradation: A novel non-canonical role of smoothened with implications in lymphoma biology. 30165192 2018
CUI: C1332206
Disease: Adult Lymphoma
Adult Lymphoma 		0.020 GeneticVariation disease BEFREE Together, these data identify a novel lymphoma-associated mutation in human BAFF-R that results in NF-κB activation and reveals TRAF6 as a necessary component of normal BAFF-R signaling. 21041452 2010