TSC1, TSC complex subunit 1, 7248

N. diseases: 391; N. variants: 155
Disease: Social Communication Disorder ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0150080
Disease: Social Communication Disorder
Social Communication Disorder 		0.010 Biomarker disease BEFREE Dysregulation of mTOR signaling has been implicated in the pathogenesis of certain types of ASD, and inhibition of mTOR by rapamycin has been demonstrated to be an effective therapeutics for impaired social interaction in Tsc1+/-, Tsc2+/-, Pten-/- mice and valproic acid-induced ASD animal models. 30816216 2019