C5, complement C5, 727

N. diseases: 129; N. variants: 20
Disease: Microscopic Polyarteritis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C2347126
Disease: Microscopic Polyarteritis
Microscopic Polyarteritis 		0.010 Biomarker disease BEFREE Phase II clinical trials of avacopan (CCX168), an orally administered C5a receptor antagonist, have suggested a reduction in the dosage of concomitant GC or the replacement of GC in patients with MPA and GPA. 30613065 2019