Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
0.090 AlteredExpression disease BEFREE Cytochrome b-c1 complex subunit 6, beta-actin, dynamin 1, and heat shock cognate 71 were up-regulated in AD+BB group, while a-enolase, stress-induced-phosphoprotein 1, malate dehydrogenase (MDH), MDH 1, and T-complex protein 1 subunit beta were down-regulated, respectively. 29781405 2020
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
0.090 AlteredExpression disease BEFREE Using a fluorophore-labeled peptide nucleic acid (PNA) attached to GO, the endogenous long noncoding RNA BC1, the constitutive protein β-actin mRNA, and miR-124a and miR-21 could be detected in the cytoplasm of a normal mouse brain, primary cultured hippocampal neurons, an Alzheimer's disease model mouse brain, and glioblastoma multiforme tumor tissues, respectively. 30594658 2019
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
0.090 AlteredExpression disease BEFREE Frequently used housekeepers such as glyceraldehyde-3-phosphate dehydrogenase (GAPDH) and β-actin had lower overall expression in AD and AD/LBD cases than in controls. 21044776 2010
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
0.090 AlteredExpression disease BEFREE In order to furnish a combined model of relevance to human inclusion-body myopathy and Alzheimer's disease, transgenic mice expressing human betaAPP-C99 in skeletal muscle and brain under the control of the cytomegalovirus/beta-actin promoter were produced (Tg13592). 15261330 2004
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
0.090 AlteredExpression disease BEFREE Further, using real-time PCR analysis, we found that beta-actin and 18S rRNA are differentially expressed in the brain specimens of both AD and control subjects, while GAPDH is similarly expressed in AD and control brain specimens. 14687679 2004
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
0.090 Biomarker disease BEFREE To assess the importance of potential confounders TaqMan real-time RT-PCR was used to measure seven mRNAs (beta-actin, glyceraldehyde-3-phosphate dehydrogenase (GAPDH), cyclophilin, microtubule-associated protein (MAP) 2, neuron-specific enolase (NSE), glial fibrillary acidic protein (GFAP), amyloid precursor protein (APP) isoform 770) in cortical samples taken from 90 Alzheimer's disease (AD) and 81 control brains. 14559355 2003
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
0.090 GeneticVariation disease BEFREE We found significantly increased DNAse I transcripts in brain of DS and AD both, when normalized versus the house-keeping gene beta actin or total RNA. 10666689 1999
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
0.090 AlteredExpression disease BEFREE The levels of peroxidation handling (CAT, GSHPx, and GSSG-R) mRNAs normalized to beta-actin mRNA level were elevated in hippocampus and inferior parietal lobule, but not in cerebellum of AD patients, which may reflect the protective gene response to the increased peroxidation in the brain regions showing severe AD pathology. 10096042 1998
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
0.090 AlteredExpression disease BEFREE The amount of nDNA-encoded beta-actin mRNA and the amount of 28S rRNA were not altered in either region of the AD brain. 9030703 1997