Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C3146251
Disease: Stage IV Colorectal Cancer AJCC v7
Stage IV Colorectal Cancer AJCC v7
0.010 AlteredExpression disease BEFREE Patients with advanced (stage IV) colorectal cancer were treated with S-1 twice daily based on the patient's body surface area (BSA; BSA < 1.25 m2, 80 mg/d; 1.25 m2 < or = BSA < 1.5 m2, 100 mg/d; BSA > or = 1.5 m2, 120 mg/d) for 28 days followed by a 2-week period rest. mRNA was isolated from paraffin-embedded pretreatment primary tumor specimens and expression levels of COX-2 relative to beta-actin as the internal reference gene were measured using a quantitative reverse transcription-PCR (Taqman) system. 15867236 2005