TNFSF4, TNF superfamily member 4, 7292

N. diseases: 129; N. variants: 32
Disease: Nasal Polyps ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0027430
Disease: Nasal Polyps
Nasal Polyps 		0.040 AlteredExpression disease BEFREE Importantly, the IL-17RB expression on mDCs and the OX40L expression on activated mDCs in NP were positively correlated with CT score and total nasal symptom score. 30519393 2018
CUI: C0027430
Disease: Nasal Polyps
Nasal Polyps 		0.040 Biomarker disease BEFREE A correlation between the number of OX40 ligand-positive cells and the number of eosinophils in sinus biopsies was found only in patients with nasal polyposis. 24583911 2015
CUI: C0027430
Disease: Nasal Polyps
Nasal Polyps 		0.040 AlteredExpression disease BEFREE Higher expression of TSLP receptor and OX40L were detected in DCs of NP nasal mucosa. 20924287 2011
CUI: C0027430
Disease: Nasal Polyps
Nasal Polyps 		0.040 Biomarker disease BEFREE The present data demonstrate that parasympathetic activity has the capacity to activate dendritic cells to release OX40 ligand, the latter induces CD4+ T cells to produce IL-4 and TNF-alpha that may further contribute to the pathogenesis of NP. 19951374 2010