TNFSF4, TNF superfamily member 4, 7292

N. diseases: 129; N. variants: 32
Disease: Hashimoto Disease ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0677607
Disease: Hashimoto Disease
Hashimoto Disease 		0.020 Biomarker disease BEFREE OX40L-JAG1-expanded Tregs showed sustained lineage stability as indicated by stable demethylation marks in Treg signature genes such as <i>Foxp3, Il2ra, Ctla4, Ikzf2,</i> and <i>Ikzf4.</i> Furthermore, OX40L-JAG1 treatment significantly increased CTLA4<sup>+</sup> and TIGIT<sup>+</sup> Tregs and alleviated experimental autoimmune thyroiditis in mice. 31704879 2019
CUI: C0677607
Disease: Hashimoto Disease
Hashimoto Disease 		0.020 Biomarker disease BEFREE TNFSF4 Gene Variations Are Related to Early-Onset Autoimmune Thyroid Diseases and Hypothyroidism of Hashimoto's Thyroiditis. 27556446 2016