TXN, thioredoxin, 7295

N. diseases: 338; N. variants: 2
Disease: Mental Depression ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0011570
Disease: Mental Depression
Mental Depression 		0.030 Biomarker disease BEFREE Our findings also indicate that thioredoxin is a potential therapeutic target for the treatment of depression. 31473777 2020
CUI: C0011570
Disease: Mental Depression
Mental Depression 		0.030 Biomarker disease BEFREE In the present study, to understand the role of thioredoxin in chronic stress and depression, we have investigated thioredoxin, thioredoxin-interacting protein, sulfenylation, nitrosylation and apoptosis signal-regulating kinase 1 phosphorylation in brain of mice exposed to chronic unpredictable stress (CUS). 30138646 2019
CUI: C0011570
Disease: Mental Depression
Mental Depression 		0.030 Biomarker disease BEFREE To date, thioredoxin (TRX), an antioxidant protein, has been investigated as a marker for psychiatric disorders such as schizophrenia, bipolar disorder and autism but its relationship with depression is yet to be unknown. 28442424 2018