TXN, thioredoxin, 7295

N. diseases: 338; N. variants: 2
Disease: Mesothelioma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0025500
Disease: Mesothelioma
Mesothelioma 		0.040 AlteredExpression disease BEFREE In the present study, we evaluated the anticancer effect of suberoylanilide hydroxamic acid (SAHA), a histone deacetylase (HDAC) inhibitor on human mesothelioma cells in relation to the levels of HDAC1, reactive oxygen species (ROS) and thioredoxin (Trx). 26936390 2016
CUI: C0025500
Disease: Mesothelioma
Mesothelioma 		0.040 Biomarker disease BEFREE Role of thioredoxin-1 in apoptosis induction by alpha-tocopheryl succinate and TNF-related apoptosis-inducing ligand in mesothelioma cells. 16647070 2006
CUI: C0025500
Disease: Mesothelioma
Mesothelioma 		0.040 Biomarker disease BEFREE Among them, the expression levels of eight genes, namely BF, FTL, IGFBP7, RARRES1, RARRES2, RBP1, SAT, and TXN according to HUGO nomenclature, were increased, whereas six: ALOX5AP, CLNS1A, EIF4A2, ELK3, REQ and SYPL, were found to be underexpressed in mesothelioma microdissected cells. 14987796 2004
CUI: C0025500
Disease: Mesothelioma
Mesothelioma 		0.040 AlteredExpression disease BEFREE Overexpression of thioredoxin might be a factor behind the poor prognosis and reduced responsiveness to therapy of mesotheliomas. 11269944 2000