TXN, thioredoxin, 7295

N. diseases: 338; N. variants: 2
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0036690
Disease: Septicemia
Septicemia
0.050 Biomarker disease BEFREE We hypothesized that TRX would be increased after trauma and associated with post-injury sepsis. 28087409 2017
CUI: C0036690
Disease: Septicemia
Septicemia
0.050 Biomarker disease BEFREE Thioredoxin-1 attenuates sepsis-induced cardiomyopathy after cecal ligation and puncture in mice. 29180214 2017
CUI: C0036690
Disease: Septicemia
Septicemia
0.050 Biomarker disease BEFREE Administration of glutathione and thioredoxin inhibitors to cell cultures enhanced HMGB1 oxidation during sepsis in endothelial and proximal tubule cells, respectively. 28806702 2017
CUI: C0036690
Disease: Septicemia
Septicemia
0.050 AlteredExpression disease BEFREE However, the decreased Bcl-2 expression in sepsis was recovered in Trx-1 Tg mice. 28505020 2017
CUI: C0036690
Disease: Septicemia
Septicemia
0.050 AlteredExpression disease BEFREE In the present study, we showed that the survival was longer in sepsis induced by cecal ligation and puncture in Trx-1 overexpression transgenic (Tg) mice compared with wild-type mice. 27299588 2016