TXNRD1, thioredoxin reductase 1, 7296

N. diseases: 136; N. variants: 21
Disease: Tuberculosis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0041296
Disease: Tuberculosis
Tuberculosis 		0.030 Biomarker disease BEFREE The short-chain dehydrogenases/reductases family (SDR) is one of a very large family of NAD- or NADP-dependent oxidoreductase enzymes which is present in all M. tuberculosis strains. 30641150 2019
CUI: C0041296
Disease: Tuberculosis
Tuberculosis 		0.030 Biomarker disease BEFREE Thus, augmenting host immune responses against Mycobacterium tuberculosis by harnessing the SET8-NQO1/TRXR1 axis with its specific and potent inhibitors could lead to promising host-directed therapeutic adjuvants for tuberculosis treatment. 28931237 2017
CUI: C0041296
Disease: Tuberculosis
Tuberculosis 		0.030 GeneticVariation disease BEFREE Association between TXNRD1 polymorphisms and anti-tuberculosis drug-induced hepatotoxicity in a prospective study. 27706680 2016