TYK2, tyrosine kinase 2, 7297

N. diseases: 172; N. variants: 22
Disease: Sarcoidosis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0036202
Disease: Sarcoidosis
Sarcoidosis 		0.110 GeneticVariation disease GWASCAT Identification of Immune-Relevant Factors Conferring Sarcoidosis Genetic Risk. 26051272 2015
CUI: C0036202
Disease: Sarcoidosis
Sarcoidosis 		0.110 GeneticVariation disease BEFREE Fourteen genes were found significantly upregulated in the cases with progressive sarcoidosis including three genes coding for effectors of the Th1 immune response: the protein tyrosine kinase TYK2, the Interferon-gamma receptor 2 and the cell cycle inhibitor p21Waf1/Cip1. 17937105 2006
CUI: C0036202
Disease: Sarcoidosis
Sarcoidosis 		0.110 AlteredExpression disease LHGDN Progressive pulmonary sarcoidosis is associated with over-expression of TYK2 and p21Waf1/Cip1. 17937105 2006