TYMS, thymidylate synthetase, 7298

N. diseases: 406; N. variants: 19
Disease: Recurrent tumor ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0521158
Disease: Recurrent tumor
Recurrent tumor 		0.020 AlteredExpression phenotype BEFREE Although TS and OPRT mRNA were not correlated with the histopathological effects and the development of tumor recurrence, DPD and TP mRNA were significantly correlated with the histopathological effects and tumor recurrence. 18986760 2009
CUI: C0521158
Disease: Recurrent tumor
Recurrent tumor 		0.020 GeneticVariation phenotype BEFREE Patients harboring the TS 3RG/+6-bp haplotype were at greatest risk to develop tumor recurrence [relative risk (RR): 2.25; 95% confidence interval (CI): 1.04-4.85; adjusted P value=0.032]. 18192902 2008