UBE2L3, ubiquitin conjugating enzyme E2 L3, 7332

N. diseases: 56; N. variants: 39
Disease: Crohn Disease ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		0.120 GeneticVariation disease GWASCAT Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease. 28067908 2017
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		0.120 GeneticVariation disease GWASCAT Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci. 26974007 2016
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		0.120 GeneticVariation disease GWASCAT Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations. 26192919 2015
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		0.120 GeneticVariation disease BEFREE In the subphenotype analysis, rs6974491-ELMO1 (P=0.0002, odds ratio (OR): 2.20) and rs2298428-UBE2L3 (P=5.44 × 10(-5), OR: 2.59) associated with pediatric UC and CD, respectively. 22592522 2012
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		0.120 GeneticVariation disease GWASDB Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci. 21102463 2010
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		0.120 GeneticVariation disease BEFREE In a combined analysis, we identified two cis-eQTL SNPs that were associated with CD rs2298428 in UBE2L3 (P=5.22x10(-5)) and rs2927488 in BCL3 (P=2.94x10(-4)). 20601676 2010
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		0.120 GeneticVariation disease GWASCAT Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci. 21102463 2010