UBE2L3, ubiquitin conjugating enzyme E2 L3, 7332

N. diseases: 56; N. variants: 39
Disease: Hepatitis B ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0019163
Disease: Hepatitis B
Hepatitis B 		0.140 GeneticVariation disease BEFREE Moreover, interferon-α (IFN-α) treatment markedly decreased UBE2L3 expression, while UBE2L3 silencing reinforced the antiviral activity of IFN-α on HBV RNAs, cccDNA, and DNA. rs59391722 in UBE2L3 was correlated with HBV DNA suppression and HBeAg loss in response to IFN-α treatment of children with CHB. 30614547 2019
CUI: C0019163
Disease: Hepatitis B
Hepatitis B 		0.140 GeneticVariation disease BEFREE The variant genotypes of rs4821116 in UBE2L3 were associated with decreased risk for HCC and chronic HBV infection. 29969176 2018
CUI: C0019163
Disease: Hepatitis B
Hepatitis B 		0.140 Biomarker disease BEFREE Other polymorphisms in or near the genes EHMT2, TCF19, and HLA-C, located near HLA class II loci, and UBE2L3 were also associated with persistent HBV infection. 26255971 2016
CUI: C0019163
Disease: Hepatitis B
Hepatitis B 		0.140 GeneticVariation disease GWASCAT New loci associated with chronic hepatitis B virus infection in Han Chinese. 24162738 2013
CUI: C0019163
Disease: Hepatitis B
Hepatitis B 		0.140 GeneticVariation disease GWASDB New loci associated with chronic hepatitis B virus infection in Han Chinese. 24162738 2013
CUI: C0019163
Disease: Hepatitis B
Hepatitis B 		0.140 Biomarker disease BEFREE These findings highlight the importance of HLA-C and UBE2L3 in the clearance of HBV infection in addition to HLA-DP and HLA-DQ. 24162738 2013