UCP3, uncoupling protein 3, 7352

N. diseases: 66; N. variants: 18
Disease: Hyperthyroidism ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0020550
Disease: Hyperthyroidism
Hyperthyroidism 		0.210 Biomarker disease RGD Using Western blots and regression analysis, we further illustrated that chronic hyperthyroidism in rats potentiates the hyperthermic effects of MDMA and increases levels of SKM UCP3 protein in a linear fashion according to levels of circulating plasma TH. 17012607 2007
CUI: C0020550
Disease: Hyperthyroidism
Hyperthyroidism 		0.210 AlteredExpression disease BEFREE Although induction of the UCP3 gene and increased protein expression during hyperthyroidism has been shown, there are no convincing data that increased UCP3 levels account for the increase in thermogenesis in the hyperthyroid state in humans. 16175492 2005