SLC35A2, solute carrier family 35 member A2, 7355

N. diseases: 197; N. variants: 18
Disease: Cholelithiasis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0008350
Disease: Cholelithiasis
Cholelithiasis 		0.040 GeneticVariation disease BEFREE Cholelithiasis has a remarkable frequency and precocity in patients with TM and especially in those with (TA)(7)/(TA)(7) UGT1-A1 genotype. 19021734 2009
CUI: C0008350
Disease: Cholelithiasis
Cholelithiasis 		0.040 GeneticVariation disease BEFREE Among the control group, the prevalence of gallstones did not differ significantly in relation to UGT1-A1 genotype, while in women carriers of beta-thalassemia it increased in an allele dose-dependent fashion. 14555305 2003
CUI: C0008350
Disease: Cholelithiasis
Cholelithiasis 		0.040 Biomarker disease BEFREE These results suggest that the UGT*1 genotpe is of importance in the genesis of gallstones in this population of patients. 11425418 2001
CUI: C0008350
Disease: Cholelithiasis
Cholelithiasis 		0.040 GeneticVariation disease BEFREE Its incidence was higher (P < 0.05) in patients homozygous for the (TA7) motif in the promoter of the UGT1-A1 gene, the genotype associated with Gilbert's syndrome, which seems to be a risk factor for the development of gallstones in TM and TI patients. 11843828 2001