UPK3A, uroplakin 3A, 7380

N. diseases: 25; N. variants: 2
Disease: Bladder Neoplasm ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0005695
Disease: Bladder Neoplasm
Bladder Neoplasm 		0.040 AlteredExpression disease BEFREE Organoids from individual BC dogs were successfully generated, expressed urothelial cell markers (CK7, CK20, and UPK3A) and exhibited tumorigenesis in vivo. 31254429 2019
CUI: C0005695
Disease: Bladder Neoplasm
Bladder Neoplasm 		0.040 Biomarker disease BEFREE We describe here the first subtype-specific murine models of bladder cancer and show that Upk3a-Cre<sup>ERT2</sup>; Trp53<sup>L/L</sup>; Pten<sup>L/L</sup>; Rosa26<sup>LSL-Luc</sup> (UPPL, luminal-like) and BBN (basal-like) tumors are more faithful to human bladder cancer than the widely used MB49 cells. 29784854 2018
CUI: C0005695
Disease: Bladder Neoplasm
Bladder Neoplasm 		0.040 AlteredExpression disease LHGDN Loss expression of uroplakin III is associated with clinicopathologic features of aggressive bladder cancer. 18313120 2008
CUI: C0005695
Disease: Bladder Neoplasm
Bladder Neoplasm 		0.040 AlteredExpression disease LHGDN Impaired p63 expression associates with poor prognosis and uroplakin III expression in invasive urothelial carcinoma of the bladder. 14654529 2003