UROD, uroporphyrinogen decarboxylase, 7389

N. diseases: 166; N. variants: 31
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0036690
Disease: Septicemia
Septicemia
0.100 Biomarker disease BEFREE According to our results the IL-18 is a biomarker better differentiating sepsis and septic shock status than PCT, CRP and WBC but with no prognostic impact. 31003186 2019
CUI: C0036690
Disease: Septicemia
Septicemia
0.100 Biomarker disease BEFREE Therefore, daily PCT measurement should not be used to predict mortality for patients with cancer and sepsis. 31284812 2019
CUI: C0036690
Disease: Septicemia
Septicemia
0.100 Biomarker disease BEFREE The aim of this study is to evaluate the diagnostic reliability of serum PCT in the diagnosis of sepsis in frail elderly patients. 30132205 2019
CUI: C0036690
Disease: Septicemia
Septicemia
0.100 Biomarker disease BEFREE A retrospective analysis of PCT and MR-proADM on 571 consecutive patients with sepsis diagnosis was performed. 31574301 2019
CUI: C0036690
Disease: Septicemia
Septicemia
0.100 Biomarker disease BEFREE We recruited SIRS (n = 33) and sepsis (n = 89) patients from electronic medical records (EMR) according to whether data on PCT, CRP, interleukin (IL)-1β, IL-2, IL-4, IL-5, IL-6, IL-9, IL-10, IL-12p70, IL-13, IL-17, IL-22, TNF-α, and IFN-γ levels were available. 30547887 2018
CUI: C0036690
Disease: Septicemia
Septicemia
0.100 Biomarker disease BEFREE Compared with the non-sepsis group, the sepsis group demonstrated significant increases in PCT but not in WBC or CRP. 29968788 2018
CUI: C0036690
Disease: Septicemia
Septicemia
0.100 Biomarker disease BEFREE Repeated measurements of the procalcitonin (PCT) biomarker are typically used for early detection and follow up of bacterial infections and sepsis, but those PCT measurements are costly. 26476896 2018
CUI: C0036690
Disease: Septicemia
Septicemia
0.100 AlteredExpression disease BEFREE Research on the diagnostic effect of PCT level in serum on patients with sepsis due to different pathogenic causes. 30024613 2018
CUI: C0036690
Disease: Septicemia
Septicemia
0.100 Biomarker disease BEFREE Concentrations of these biomarkers in function of sepsis severity (sepsis n = 94 and septic shock n = 21) and outcome (lethal n = 40, recovery n = 75) were tested, as well as correlations with APACHE II and SOFA scores, immunoglobulins, complement, PCT and CRP concentrations. 30142533 2018
CUI: C0036690
Disease: Septicemia
Septicemia
0.100 AlteredExpression disease BEFREE In the literature, there are just few data about the association between PCT levels and endocarditis and sepsis but there are not etiological differentiations particularly for those sustained by Streptococcus viridans. 28387901 2017
CUI: C0036690
Disease: Septicemia
Septicemia
0.100 Biomarker disease BEFREE In conclusion, 1,25(OH)D but not 25(OH)D showed a minor discriminatory value for the prediction of bacteraemia that was inferior to CRP and PCT but both failed to predict sepsis and mortality in a prospective cohort of SIRS patients. 28079172 2017
CUI: C0036690
Disease: Septicemia
Septicemia
0.100 AlteredExpression disease BEFREE The CRP and PCT protein expression results of the sepsis patients were higher than those of the control group. 28962140 2017
CUI: C0036690
Disease: Septicemia
Septicemia
0.100 Biomarker disease BEFREE The area under ROC curve showed that the clinical accuracy of microRNA-25 for sepsis diagnosis was better than CRP and PCT (AUG=0.806, 0.676 and 0.726, P<0.05).The decrease in level of microRNA-25 was correlated with the severity of sepsis, SOFA score, CRP and PCT level, meanwhile, microRNA-25 level can be used for predicting the prognosis of patients, the patients with microRNA-25 level ≤0.492 had a lower 28 d survival rate. 26339334 2015
CUI: C0036690
Disease: Septicemia
Septicemia
0.100 Biomarker disease BEFREE The present study is the first to demonstrate the decreased expression of CRISPLD2 in septic shock and its association with PCT in sepsis. 23799041 2013