VCAM1, vascular cell adhesion molecule 1, 7412

N. diseases: 406; N. variants: 9
Disease: Sjogren's Syndrome ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1527336
Disease: Sjogren's Syndrome
Sjogren's Syndrome 		0.030 AlteredExpression disease BEFREE The levels of sICAM-1 in pSS and sVCAM-1 in sSS patients were significantly higher when compared to HS (p = 0.02 and p = 0.048, respectively). 29068581 2017
CUI: C1527336
Disease: Sjogren's Syndrome
Sjogren's Syndrome 		0.030 Biomarker disease BEFREE Although no association has been found with the NF-kB gene itself, associations in TNFAIP3 and TNIP1 (both genome-wide significant), VCAM1 and IRAK1BP (both suggestive), point to genetic explanations for dysregulation of the NF-kB pathway in SS. 27431346 2016
CUI: C1527336
Disease: Sjogren's Syndrome
Sjogren's Syndrome 		0.030 AlteredExpression disease BEFREE Cytokine-mediated up-regulation of VCAM-1 and ICAM-1 that facilitates the recruitment of VLA-4 and LFA-1 expressing T cells might contribute to lymphoid cell infiltration in the salivary and lacrimal glands in SS. 8509947 1993