|
Osteosarcoma
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
The results from this study suggest that VEGF genetic variants are potentially related to OS susceptibility in Chinese Han population and might be used as molecular markers for assessing OS susceptibility.
|
24310504 |
2014 |
|
Osteosarcoma
|
0.400 |
Biomarker
|
disease |
BEFREE |
miR-1 Inhibits Cell Growth, Migration, and Invasion by Targeting VEGFA in Osteosarcoma Cells.
|
27777493 |
2016 |
|
Osteosarcoma
|
0.400 |
Biomarker
|
disease |
BEFREE |
However the impact of VEGFA gene amplification has been only recently assessed for some cancer types such as osteosarcoma, colorectal, breast and liver cancer.
|
24114200 |
2014 |
|
Osteosarcoma
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
The aim of this study was to determine the prognostic significance of blood VEGF and blood and urinary basic fibroblast growth factor (bFGF) levels in osteosarcoma patients, both at diagnosis and during treatment.
|
28619014 |
2017 |
|
Osteosarcoma
|
0.400 |
Biomarker
|
disease |
BEFREE |
Taken together, our data demonstrate that VEGF silencing suppresses cell proliferation, promotes cell apoptosis, and reduces osteosarcoma angiogenesis through inactivation of PI3K/AKT signaling pathway.
|
27352347 |
2015 |
|
Osteosarcoma
|
0.400 |
Biomarker
|
disease |
BEFREE |
Simultaneous silencing of VEGF and Survivin using the dual siRNA may be an advantageous alternative for the development of therapeutic strategies against human osteosarcoma.
|
30566604 |
2019 |
|
Osteosarcoma
|
0.400 |
Biomarker
|
disease |
BEFREE |
Epigenetic modulators hydralazine and sodium valproate act synergistically in VEGI-mediated anti-angiogenesis and VEGF interference in human osteosarcoma and vascular endothelial cells.
|
31180533 |
2019 |
|
Osteosarcoma
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
In the present study, the effects of IRX2 on the upregulation of MMP2 and VEGF in OS were determined by western blotting, and the underlying molecular mechanisms were elucidated.
|
26062523 |
2015 |
|
Osteosarcoma
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
In this study, we investigated the effects of PEDF on growth and vascular endothelial growth factor (VEGF) expression in MG63 human cultured osteosarcoma cells.
|
15985268 |
2005 |
|
Osteosarcoma
|
0.400 |
Biomarker
|
disease |
BEFREE |
In conclusion, YY1 and VEGF/CXCR4 seem to intervene in the pathogenesis of the malignant phenotype of osteosarcoma by acting on cell invasiveness and metastasis growth.
|
18339860 |
2008 |
|
Osteosarcoma
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
In the present study, we reported the higher expression of vascular endothelial growth factor‑A (VEGF‑A) in osteosarcoma cells that were resistant to anoikis than in parental osteosarcoma cells, promoting the proliferation, tube formation, and migration of human umbilical vein endothelial cells (HUVECs).
|
30542722 |
2019 |
|
Osteosarcoma
|
0.400 |
Biomarker
|
disease |
BEFREE |
Here, we investigate the role of α-CaMKII-induced VEGF in the growth and tumorigenicity of OS.
|
25860662 |
2015 |
|
Osteosarcoma
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
Effect of cortisol on cell proliferation and the expression of lipoprotein lipase and vascular endothelial growth factor in a human osteosarcoma cell line.
|
17549480 |
2008 |
|
Osteosarcoma
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Single nucleotide polymorphisms in VEGF gene are associated with an increased risk of osteosarcoma.
|
25550863 |
2014 |
|
Osteosarcoma
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
In summary, this study found that the VEGF -634G/C gene polymorphism was associated with an increased risk of osteosarcoma.
|
26345754 |
2015 |
|
Osteosarcoma
|
0.400 |
Biomarker
|
disease |
CTD_human |
Angiogenesis plays a role in the progression of osteosarcoma, as well as in other mesenchymal tumors and carcinomas, and it is most commonly assessed by vascular endothelial growth factor (VEGF) expression or tumor CD31-positive microvessel density (MVD).
|
20158913 |
2010 |
|
Osteosarcoma
|
0.400 |
AlteredExpression
|
disease |
LHGDN |
Samples from osteosarcoma patients were assessed for HIF-1alpha and VEGF protein expression using immunohistochemistry, neovascularization using antibodies for Factor VIII, and cell proliferation using the Ki-67 labeling index.
|
18528739 |
2008 |
|
Osteosarcoma
|
0.400 |
AlteredExpression
|
disease |
LHGDN |
CXCR4 and VEGF expression in the primary site and the metastatic site of human osteosarcoma: analysis within a group of patients, all of whom developed lung metastasis.
|
16528367 |
2006 |
|
Osteosarcoma
|
0.400 |
AlteredExpression
|
disease |
LHGDN |
VEGF gene might be closely related to the apoptosis and proliferation of osteosarcoma cells, and appears to be crucial for formation of vasculogenic mimicry in osteosarcoma.
|
18438338 |
2008 |