VIL1, villin 1, 7429

N. diseases: 32; N. variants: 5
Disease: Kidney Failure, Chronic ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic 		0.010 GeneticVariation disease BEFREE By systematically characterizing the mouse model, we found that Pkd2<sup>f3/f3</sup> mice with a Cre transgene driven by the mouse villin-1 promoter (Vil-Cre;Pkd2<sup>f3/f3</sup> ) develop overt cysts in the kidney, liver and pancreas and die of end-stage renal disease (ESRD) at 4-6 months of age. 28244683 2017