VIM, vimentin, 7431

N. diseases: 644; N. variants: 6
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1608408
Disease: Malignant transformation
Malignant transformation
0.020 Biomarker phenotype BEFREE PARP-1 regulates metastatic melanoma through modulation of vimentin-induced malignant transformation. 23785295 2013
CUI: C1608408
Disease: Malignant transformation
Malignant transformation
0.020 Biomarker phenotype BEFREE Our results indicate that the cell motility enhancing effect of HER-2/neu oncoprotein and possibly vimentin plays a significant role in the pathogenesis of MPD which appears to be a pagetoid spread of an underlying ductal malignancy (secondary), while EPD is an in situ malignant transformation of a totipotential epidermal cell or glandular epithelium. 14616943 2004