VIM, vimentin, 7431

N. diseases: 644; N. variants: 6
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Malignant neoplasm of colon and/or rectum
0.100 Biomarker disease BEFREE The analysis of protein expression in 114 human colorectal cancer tissues demonstrated that the expressions of SphK1, FAK, phosphorylated (p)‑FAK, E‑cadherin and vimentin were associated with the metastasis of colorectal cancer. 30365116 2019
Malignant neoplasm of colon and/or rectum
0.100 AlteredExpression disease BEFREE Co-expression of cytokeratin and vimentin in colorectal cancer highlights a subset of tumor buds and an atypical cancer-associated stroma. 30794893 2019
Malignant neoplasm of colon and/or rectum
0.100 Biomarker disease BEFREE FSTL1 interacts with VIM and promotes colorectal cancer metastasis via activating the focal adhesion signalling pathway. 29844309 2018
Malignant neoplasm of colon and/or rectum
0.100 PosttranslationalModification disease BEFREE LncRNA FTX sponges miR-215 and inhibits phosphorylation of vimentin for promoting colorectal cancer progression. 29925853 2018
Malignant neoplasm of colon and/or rectum
0.100 Biomarker disease BEFREE The aim of the present study was to evaluate the aberrant gain of methylation in the gene promoters of VIM, TFPI2 and ITGA4 as putative early markers in the development from inflamed tissue via precancerous lesions toward colorectal cancer. 25902909 2015
Malignant neoplasm of colon and/or rectum
0.100 Biomarker disease BEFREE Pathway reconstruction and protein-protein networking of identified proteins predicted only Vimentin to be physically and genetically engaged in close proximity with the most established colorectal cancer associated tumorigenic pathways. 25319351 2015
Malignant neoplasm of colon and/or rectum
0.100 PosttranslationalModification disease BEFREE Serum vimentin methylation as a potential marker for colorectal cancer. 25075038 2014
Malignant neoplasm of colon and/or rectum
0.100 Biomarker disease BEFREE Increased expression of Slug and Vimentin as novel predictive biomarkers for lymph node metastasis and poor prognosis in colorectal cancer. 24001454 2013
Malignant neoplasm of colon and/or rectum
0.100 Biomarker disease BEFREE Detection of hypermethylated vimentin in urine of patients with colorectal cancer. 22251609 2012
Malignant neoplasm of colon and/or rectum
0.100 PosttranslationalModification disease BEFREE Interestingly, methylation was significantly found in the serum of patients with liver metastasis, peritoneal dissemination, and distant metastasis (p = 0.026, p = 0.0029 and p = 0.0063, respectively), suggesting that vimentin methylation in serum might be detected more frequently in patients with advanced colorectal cancer. 21187483 2010
Malignant neoplasm of colon and/or rectum
0.100 AlteredExpression disease BEFREE The methylated methylguanine DNA methyltransferase, human Mut L homolog-1, and vimentin were detected in 51.7%, 30.0%, and 38.3% of colorectal cancer, and in 36.5%, 11.%, and 15.4% of colorectal adenomas, respectively. 19617759 2009
Malignant neoplasm of colon and/or rectum
0.100 PosttranslationalModification disease BEFREE The methylation status of the Vimentin gene was examined in primary carcinomas and the corresponding normal tissues derived from 48 patients with colorectal cancer using quantitative methylation-specific PCR (qMSP) and the correlation between the methylation status and the clinicopathological findings was evaluated. 19331162 2009
Malignant neoplasm of colon and/or rectum
0.100 Biomarker disease BEFREE Four genes specifically methylated in colorectal cancer [bone morphogenetic protein 3 (BMP3), EYA2, aristaless-like homeobox-4 (ALX4), and vimentin] were selected from 41 candidate genes and evaluated on 74 cancers, 62 adenomas, and 70 normal epithelia. 18086775 2007