|
CATARACT 30
|
0.800 |
GeneticVariation
|
disease |
UNIPROT |
Targeted Exome Sequencing of Congenital Cataracts Related Genes: Broadening the Mutation Spectrum and Genotype-Phenotype Correlations in 27 Chinese Han Families.
|
28450710 |
2017 |
|
CATARACT 30
|
0.800 |
GeneticVariation
|
disease |
UNIPROT |
Sporadic and Familial Congenital Cataracts: Mutational Spectrum and New Diagnoses Using Next-Generation Sequencing.
|
26694549 |
2016 |
|
CATARACT 30
|
0.800 |
Biomarker
|
disease |
GENOMICS_ENGLAND |
Defect of mitotic vimentin phosphorylation causes microophthalmia and cataract via aneuploidy and senescence in lens epithelial cells.
|
24142690 |
2013 |
|
CATARACT 30
|
0.800 |
GeneticVariation
|
disease |
UNIPROT |
Dominant cataract formation in association with a vimentin assembly disrupting mutation.
|
19126778 |
2009 |
|
CATARACT 30
|
0.800 |
CausalMutation
|
disease |
CLINVAR |
|
|
|
|
CATARACT 30
|
0.800 |
Biomarker
|
disease |
GENOMICS_ENGLAND |
|
|
|
|
CATARACT 30
|
0.800 |
Biomarker
|
disease |
MGD |
|
|
|
|
Cataract, Pulverulent
|
0.600 |
GermlineCausalMutation
|
disease |
ORPHANET |
Here, we demonstrate that a mutation in VIM causes a dominant, pulverulent cataract.
|
19126778 |
2009 |
|
Cataract, Pulverulent
|
0.600 |
Biomarker
|
disease |
MGD |
|
|
|
|
Cataract, Pulverulent
|
0.600 |
Biomarker
|
disease |
HPO |
|
|
|
|
CATARACT, COPPOCK-LIKE
|
0.500 |
GermlineCausalMutation
|
disease |
ORPHANET |
Dominant cataract formation in association with a vimentin assembly disrupting mutation.
|
19126778 |
2009 |
|
Nephrosis
|
0.500 |
Biomarker
|
disease |
RGD |
To gain insight into the role of IF proteins in podocytes, we investigated the expression of nestin, vimentin, and desmin in puromycin aminonucleoside (PAN) nephrosis.
|
16418842 |
2006 |
|
Nephrosis
|
0.500 |
Biomarker
|
disease |
CTD_human |
To gain insight into the role of IF proteins in podocytes, we investigated the expression of nestin, vimentin, and desmin in puromycin aminonucleoside (PAN) nephrosis.
|
16418842 |
2006 |
|
CATARACT, COPPOCK-LIKE
|
0.500 |
Biomarker
|
disease |
MGD |
|
|
|
|
Malignant neoplasm of breast
|
0.400 |
Biomarker
|
disease |
BEFREE |
EpCAM overexpression increases the expression of stemness markers (NANOG，SOX2, and OCT4) and EMT markers (N-cadherin and vimentin) under the condition of hypoxia in BC.
|
31584203 |
2020 |
|
Neoplasm Metastasis
|
0.400 |
AlteredExpression
|
phenotype |
BEFREE |
Silencing of MPP8 also decreased the expression of metastasis pathway-related proteins (N-cadherin and vimentin), and as well as the levels of anti-oncogene ZEB1, MET, and KRAS mRNA.
|
31692032 |
2020 |
|
Neoplasm Metastasis
|
0.400 |
Biomarker
|
phenotype |
BEFREE |
lncRNA VIM-AS1 was overexpressed in PCa tissues and cell lines and promoted PCa proliferation and metastasis via EMT through regulating vimentin, which might provide a novel target for the diagnosis and therapy for PCa.
|
31786880 |
2020 |
|
Neoplasm Metastasis
|
0.400 |
AlteredExpression
|
phenotype |
BEFREE |
Moreover, CARM1- and USP7-dependent LSD1 stabilization plays a key role in repressing E-cadherin and activating vimentin transcription through promoter H3K4me2 and H3K9me2 demethylation, respectively, which promotes invasion and metastasis of breast cancer cells.
|
31833203 |
2020 |
|
Malignant neoplasm of prostate
|
0.400 |
Biomarker
|
disease |
BEFREE |
This ability of hsa-miR-200c to reclaim epithelial traits leads to the anticipation that molecular reprogramming of Zeb1-Slug/vimentin axis may relieve aggressiveness of prostate cancer.
|
31759982 |
2020 |
|
Breast Carcinoma
|
0.400 |
Biomarker
|
disease |
BEFREE |
EpCAM overexpression increases the expression of stemness markers (NANOG，SOX2, and OCT4) and EMT markers (N-cadherin and vimentin) under the condition of hypoxia in BC.
|
31584203 |
2020 |
|
Malignant neoplasm of breast
|
0.400 |
Biomarker
|
disease |
BEFREE |
COPB2 is up-regulated in breast cancer and plays a vital role in the metastasis via N-cadherin and Vimentin.
|
31119859 |
2019 |
|
Malignant neoplasm of breast
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
In our study, MAP2K4 and Vimentin co-expression is confirmed to be an unfavorable factor in breast cancer.
|
31761784 |
2019 |
|
Malignant neoplasm of breast
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
Also, luteolin impeded TGFβ1-induced EMT, as evidenced by the decreased levels of Vimentin, Zeb1 and N-cadherin, as well as the increased level of E-cadherin. miR-203 was highly expressed in 22 pair of breast cancer tissues than the matched paracancerous tissues.Luteolin could elevate miR-203 level.
|
31368817 |
2019 |
|
Malignant neoplasm of breast
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
We observed that the response of cultured breast cancer primary cells to MTF varied; mesenchymal cells were resistant to 10 mM MTF and expressed Vimentin and SNAIL, which are associated with a mesenchymal phenotype, whereas epithelial cells were sensitive to this MTF dose, and expressed E-cadherin but not mesenchymal markers.
|
31337349 |
2019 |
|
Malignant neoplasm of breast
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
PITX2, Wnt-1, β-catenin, N-cadherin, and vimentin all displayed higher levels, while miR-590-5p and E-cadherin expression were lower among breast cancer tissues than in the adjacent normal tissue.
|
30191949 |
2019 |