Disease: Mental Depression ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0011570
Disease: Mental Depression
Mental Depression 		0.050 Biomarker disease BEFREE Preclinical studies found that TRPV1 mediates behaviors associated with anxiety and depression. 31814000 2020
CUI: C0011570
Disease: Mental Depression
Mental Depression 		0.050 Biomarker disease BEFREE TRPV1 can trigger glutamate release and nitric oxide synthesis in the brain, mechanisms also involved in the neurobiology of depression. 30299277 2019
CUI: C0011570
Disease: Mental Depression
Mental Depression 		0.050 Biomarker disease BEFREE Transient receptor potential vanilloid 1 (TRPV1) channels have been implicated in depression and anxiety. 30138635 2018
CUI: C0011570
Disease: Mental Depression
Mental Depression 		0.050 Biomarker disease BEFREE The shortening of C4 inspiratory burst by eugenol was not reversed by capsazepine (TRPV1 antagonist) or HC-030031 (TRPA1 antagonist), whereas the depression was partially blocked by GABA<sub>A</sub> antagonist bicuculline and glycine antagonist strychnine or GABA<sub>B</sub> antagonist phaclofen. 28963585 2018
CUI: C0011570
Disease: Mental Depression
Mental Depression 		0.050 Biomarker disease BEFREE Our data indicate that capsaicin-induced modulation of LA-LTP via TRPV1 involves GluA1-containing AMPARs whereas capsaicin-induced modulation of LA-LTD via TRPM1 is independent of the expression of the AMPAR GluA1 subunit. 29246976 2018