|
Sepsis
|
0.100 |
Biomarker
|
disease |
BEFREE |
We studied the role of VWF and ADAMTS13 in S. aureus sepsis both in patients and in mice.
|
31758651 |
2020 |
|
Sepsis
|
0.100 |
Biomarker
|
disease |
BEFREE |
Four latent factors (Factor 1-4) were identified, each potentially representing distinct biological processes for the endothelial response to sepsis: Factor 1 (CHI3L1, sTREM1, sFLT1); Factor 2 (ANGPT1, PF4, VEGF); Factor 3 (CXCL10, VWF, sICAM1); and Factor 4 (ANGPT2, sTEK).
|
31013257 |
2019 |
|
Sepsis
|
0.100 |
Biomarker
|
disease |
BEFREE |
The purpose of this study was to quantify measures of endothelial function, including markers of activation (endocan, Angiopoietin-2 [Ang-2], and von Willebrand Factor), endogenous anticoagulants (tissue factor pathway inhibitor and protein C), and damage-associated factors (High Mobility Group Box 1 [HMGB-1]) in the plasma of patients with sepsis and DIC, and to determine the relationship of these factors with severity of illness and outcome.
|
31140293 |
2019 |
|
Sepsis
|
0.100 |
Biomarker
|
disease |
BEFREE |
Consecutive ACLF patients without sepsis at baseline were assessed at days 0, 3 and 7 with thromboelastography (TEG) and specific assays (Factor VIII, von Willebrand factor [vWF], protein C and antithrombin III [ATIII]) and followed for development of sepsis, bleeding and outcome.
|
30589495 |
2019 |
|
Sepsis
|
0.100 |
Biomarker
|
disease |
BEFREE |
Risk stratification and prognostic evaluation of endothelial cell-specific molecule1, von Willebrand factor, and a disintegrin-like and metalloprotease with thrombospondin type 1 motif for sepsis in the emergency department: An observational study.
|
31086585 |
2019 |
|
Sepsis
|
0.100 |
Biomarker
|
disease |
BEFREE |
The thrombomodulin/protein C and VWF/ADAMTS-13 pathways are disturbed in sepsis and have been implicated in the coagulation disorders that characterize the septic syndrome.
|
30159948 |
2018 |
|
Sepsis
|
0.100 |
Biomarker
|
disease |
BEFREE |
In addition, we discuss the possible benefit of restoring ADAMTS-13 levels or reducing the effect of ultralarge VWF as an adjunctive treatment in patients with sepsis.
|
29337416 |
2018 |
|
Sepsis
|
0.100 |
Biomarker
|
disease |
BEFREE |
We examine the GP Ib-IX/von Willebrand factor axis in murine polymicrobial sepsis, as modeled by cecal ligation and puncture (CLP).
|
24504734 |
2014 |
|
Sepsis
|
0.100 |
Biomarker
|
disease |
BEFREE |
We investigated the role of ADAMTS13 and VWF in the severity and outcome of sepsis.
|
20390223 |
2010 |
|
Sepsis
|
0.100 |
AlteredExpression
|
disease |
LHGDN |
ADAMTS-13, von Willebrand factor and related parameters in severe sepsis and septic shock.
|
17764538 |
2007 |