WAS, WASP actin nucleation promoting factor, 7454

N. diseases: 204; N. variants: 37
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0007370
Disease: Catalepsy
Catalepsy
0.030 Biomarker disease BEFREE WIN55,212-2 and Δ-9-THC produced antinociception as well as hypomotility, catalepsy and motor impairment. 31311288 2020
CUI: C0007370
Disease: Catalepsy
Catalepsy
0.030 Biomarker disease BEFREE Specifically, our meta-analysis investigated: (i) the alleged bidirectional effects and dose-dependence of Δ<sup>9</sup>-THC in the PC test; (ii) methodological inconsistencies between PC studies; and (iii) other pharmacological studies on cannabinoids (i.e., dopamine release, anxiety, stress, conditioned taste aversion, catalepsy) to substantiate the validity of PC findings. 30115766 2018
CUI: C0007370
Disease: Catalepsy
Catalepsy
0.030 Biomarker disease BEFREE Synthetic cannabinoids (0.01-6 mg/kg i.p.) impaired motor activity and induced catalepsy in mice and their effects were more severe with respect to those evoked by Δ(9)-THC. 25769232 2015