WNT1, Wnt family member 1, 7471

N. diseases: 216; N. variants: 12
Disease: Diabetes ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0011847
Disease: Diabetes
Diabetes 		0.020 Biomarker disease BEFREE On the other hand, it is documented that diabetes leads to overactivation of Wnt1/β-catenin signaling, which promotes podocyte injury, induce epithelial-mesenchymal transition of podocytes along with renal injury and fibrosis. 30935943 2019
CUI: C0011847
Disease: Diabetes
Diabetes 		0.020 AlteredExpression disease BEFREE Therefore, the results of the present study indicated that treatment with TW mitigated hyperglycemia-induced upregulated Wnt-1 and β-catenin expression in kidney tissues and ameliorated diabetes-induced kidney injury in rats. 29581743 2018