WNT7B, Wnt family member 7B, 7477

N. diseases: 53; N. variants: 5
Disease: Myopia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0027092
Disease: Myopia
Myopia 		0.020 GeneticVariation disease BEFREE WNT7B SNPs located in the same genomic region that includes rs9330813 have previously been associated with CCT in Latinos but with other ocular quantitative traits related to myopia (corneal curvature and axial length) in a Japanese population (rs10453441 and rs200329677). 29847655 2018
CUI: C0027092
Disease: Myopia
Myopia 		0.020 AlteredExpression disease BEFREE We also find in a mouse model of myopia downregulation of WNT7B expression in the cornea and upregulation in the retina, suggesting its possible role in the development of myopia. 25823570 2015