WNT10B, Wnt family member 10B, 7480

N. diseases: 90; N. variants: 23
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.050 Biomarker phenotype BEFREE The WNT10B Network Is Associated with Survival and Metastases in Chemoresistant Triple-Negative Breast Cancer. 30563890 2019
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.050 AlteredExpression phenotype BEFREE In contrast, RNA-seq data set of annotated human PCa metastasis found a significant increase in WNT10B mRNA expression compared with localized tumors suggesting stage-specific functions of WNT10B. 31433503 2019
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.050 Biomarker phenotype BEFREE We provided substantive evidence that FABP4 is a growth and metastasis promoter in vivo and revealed that it functions in part through Wnt10b, which suggests that FABP4 might act as a probable target to block glioblastoma metastasis. 30536325 2018
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.050 Biomarker phenotype BEFREE Aberrant low expression of p85α in stromal fibroblasts promotes breast cancer cell metastasis through exosome-mediated paracrine Wnt10b. 28394344 2017
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.050 AlteredExpression phenotype BEFREE The difference in Wnt10b levels was significant among subgroups for histological type, grade of differentiation, FIGO phase and lymphovascular metastasis. 23135473 2013