WNT10B, Wnt family member 10B, 7480

N. diseases: 90; N. variants: 23
Disease: Endometrial Carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0476089
Disease: Endometrial Carcinoma
Endometrial Carcinoma 		0.050 AlteredExpression disease BEFREE By co-culture IP assay, we demonstrated that SMOC-2 directly interacted with WNT receptors (Fzd6 and LRP6), enhanced ligand-receptor interaction with canonical WNT ligands (Wnt3a and Wnt10b), and finally, activated the WNT/β-catenin pathway in endometrial cancer. 30594556 2019
CUI: C0476089
Disease: Endometrial Carcinoma
Endometrial Carcinoma 		0.050 Biomarker disease BEFREE It can be concluded that Wnt10b gene can promote EC cell proliferation and inhibit its apoptosis. 27358147 2016
CUI: C0476089
Disease: Endometrial Carcinoma
Endometrial Carcinoma 		0.050 AlteredExpression disease BEFREE In the follow-up, Wnt10b gene expression was frequently upregulated in EC and associated with better prognostic clinicopathological markers in EC patients. 23135473 2013
CUI: C0476089
Disease: Endometrial Carcinoma
Endometrial Carcinoma 		0.050 Biomarker disease BEFREE In contrast to the effect of miR-148a, WNT10B stimulated migration of endometrial cancer cell lines. 22890324 2013
CUI: C0476089
Disease: Endometrial Carcinoma
Endometrial Carcinoma 		0.050 AlteredExpression disease BEFREE In fresh tissues, all Wnt genes apart from Wnt10b were expressed in normal endometrium and endometrial carcinoma. 9099960 1997