WT1, WT1 transcription factor, 7490

N. diseases: 446; N. variants: 61
Disease: Renal glomerular disease ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0268731
Disease: Renal glomerular disease
Renal glomerular disease 		0.420 GeneticVariation group BEFREE Denys-Drash syndrome (DDS), caused by mutations in the WT1 gene affecting the third or second zinc finger, is characterized by a triad of glomerulopathy progressing rapidly to end-stage renal disease, male hermaphroditism, and Wilms tumor. 17533022 2007
CUI: C0268731
Disease: Renal glomerular disease
Renal glomerular disease 		0.420 GeneticVariation group BEFREE The WT1 gene encodes a zinc finger transcription factor involved in kidney and gonadal development and, when mutated, in the occurrence of kidney tumor and glomerular diseases. 16927106 2006
CUI: C0268731
Disease: Renal glomerular disease
Renal glomerular disease 		0.420 Biomarker group GENOMICS_ENGLAND
CUI: C0268731
Disease: Renal glomerular disease
Renal glomerular disease 		0.420 Biomarker group HPO