XBP1, X-box binding protein 1, 7494

N. diseases: 234; N. variants: 6
Disease: Adenocarcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma 		0.040 Biomarker group BEFREE In contrast, knockdown of XBP1 inhibits myotube atrophy in response to LLC or C26 adenocarcinoma cell conditioned medium. 31138662 2019
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma 		0.040 AlteredExpression group BEFREE Using stored tissues, we examined (i) the percentage of a splicing form (active form) of XBP1 messenger RNA in normal lung tissue (NLT) and adenocarcinoma (ACA; using reverse-transcription polymerase chain reaction); (ii) ATF6 and GRP78 protein expressions in NLT and ACA (using Western blotting analysis); (iii) ATF6, XBP1, and GRP78 protein expressions in NLT, AAH, and ACA, including some adenocarcinoma in situ (using immunohistochemistry); and (iv) the incidence of nuclear translocation of the 3 proteins in these lesions. 30121368 2019
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma 		0.040 Biomarker group BEFREE 395 human breast adenocarcinomas were immunohistochemically stained for UPR activation markers (glucose-regulated protein (GRP-78 and XBP-1). 19861963 2009
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma 		0.040 AlteredExpression group LHGDN Down-regulation of human X-box binding protein 1 (hXBP-1) expression correlates with tumor progression in human prostate cancers. 11813207 2002