XBP1, X-box binding protein 1, 7494

N. diseases: 234; N. variants: 6
Disease: Asthma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0004096
Disease: Asthma
Asthma 		0.020 Biomarker disease BEFREE Here, we investigated the role of the IRE1a-XBP1 pathway in regulating activation and differentiation of type-2 T helper cell (Th2), a major T helper cell type involved in allergy, asthma, helminth infection, pregnancy, and tumor immunosuppression. 30355343 2018
CUI: C0004096
Disease: Asthma
Asthma 		0.020 Biomarker disease BEFREE ER stress was confirmed by an increase in XBP1 (X-box binding protein 1) splicing in mild asthma and was associated with both type 2 inflammation and ISG expression. 29064281 2018